A single course of rituximab does not abrogate anti-infliximab antibodies in patients with rheumatoid arthritis.
نویسندگان
چکیده
Ann Rheum Dis 2009;68:1367–1368. doi:10.1136/ard.2008.099093 REFERENCES 1. Mladenovic V, Domljan Z, Rozman B, Jajic I, Mihajlovic D, Dordevic J, et al. Safety and effectiveness of leflunomide in the treatment of patients with active rheumatoid arthritis. Results of a randomized, placebo-controlled, phase II study. Arthritis Rheum 1995;38:1595–603. 2. Kalgutkar AS, Nguyen HT, Vaz AD, Doan A, Dalvie DK, McLeod DG, et al. In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes. Drug Metab Dispos 2003;31:1240–50. 3. Bohanec Grabar P, Rozman B, Tomsic M, Suput D, Logar D, Dolzan V. Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients. Eur J Clin Pharmacol 2008:64:871–6. 4. Breedveld FC, Dayer JM. Leflunomide: mode of action in the treatment of rheumatoid arthritis. Ann Rheum Dis 2000;59:841–9. 5. Chonlahan J, Halloran MA, Hammonds A. Leflunomide and warfarin interaction: case report and review of the literature. Pharmacotherapy 2006;26:868–71. 6. Lim V, Pande I. Leflunomide can potentiate the anticoagulant effect of warfarin. BMJ 2002;325:1333. 7. Sevilla-Mantilla C, Ortega L, Agundez JA, Fernandez-Gutierrez B, Ladero JM, DiazRubio M. Leflunomide-induced acute hepatitis. Dig Liver Dis 2004;36:82–4.
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 68 8 شماره
صفحات -
تاریخ انتشار 2009